Estudo
comparativo de duas formas de permeação
cutânea ativa na redução da gordura
localizada
Conclusão
Neste trabalho
podemos concluir que o método da permeação
transcutânea ativa tem utilidade no tratamento
auxiliar da gordura localizada, devendo porém,
seus mecanismos de ação serem ainda
melhor elucidados.
Bibliografia
Consultada
1 - Barry, WB,; Novel
mechanisms and devices to enable successful, transdermal
drug delivery - European Journal of Pharmaceutical
Sciences, 2001; 14 : 101-114
2 - Bonmannan R. L. et al - Sonophoresis I - The Use
of High Frequency Ultrasound
to Enhance Transdermal Drug Delivery - Pharmaceutical
Research , 1 992; 9 :441-834
3 - Bronaugh R.L. et al - Percutaneous Absorption
- Drugs - Cosmetics -
Mechanisms - Methodology - Third edition - volume
97, Marcel Dekker, Inc - New York.
4 - Flynn, GL,; TopicaL drug absorption and topical
pharmaceutical system in:
Banker, GS,; Rhodes, CT., eds. Modern pharmaceutics.
New York Marcel
Dekker, 1990: 263 - 325.
5 - Gaertner, W. - Frequency dependence of ultrasonic
cavitation - The Journal of
the Acoustical Society of America, November 1954,
26 ( 4 ): 977.
6 - James E. Young - Transmission of Sound through
thin elastic plates - The
Journal of the Acoustical Society of America, July
1954; 26 ( 4 ) : 485.
7 - Johnson, Mark E. et al - Chemical and physical
enhancers and ultrasound for
transdermal drug delivery - Massachussets Institute
of Technology - US
Patent 5,947, 921.
8 - Macias, CF.; Macias, CC.; Uso de antiinflamatórios
esteróides por via oral vc
por iontoforesis, Lilacs, 1998; 4 ( 1 ): 32 - 34.
9 - Manual do fabricante - Mesotron M-2000 med - MEDWORKS
- Jan/2003.
10- Matsuda, H,; Arima, H.; Cyclodextrins in transdermal
and rectal delivery . Adv. Drug Delivery Ver. Amsterdam,
1987; 6; 85 - 99.
11- Mitragotri. S. et al - A Mechanistic Study of
Ultrasonically enhanced
Transdermal Drug Delivery - Journal of Pharmaceutical
Sciences - June
1995; 84 ( 6 ): 697.
12- Saad, M.: Atlas, S; Fonofonese: revisão
de literatura. Med reab, 1985; 41: 7-10.
13- Tezel A . et al - Frequency dependence of Sonophoresis
- Pharmaceutical
Research, Dec 2001; 18 ( 12 ): 1694.
14- Tezel A . et al - Investigations of The Role of
Cavitation in LF Sonophoresis
Using Acoustic Spectroscopy - Journal of Pharmaceutical
Sciences, Feb
2002; 91 ( 2 )
